https://w3id.org/np/RA3o90XgFx_gbp6k69qT8WA1MaaEFwaILFWnfwEJ4_v7k/Head https://w3id.org/np/RA3o90XgFx_gbp6k69qT8WA1MaaEFwaILFWnfwEJ4_v7k http://www.nanopub.org/nschema#hasAssertion https://w3id.org/np/RA3o90XgFx_gbp6k69qT8WA1MaaEFwaILFWnfwEJ4_v7k/assertion https://w3id.org/np/RA3o90XgFx_gbp6k69qT8WA1MaaEFwaILFWnfwEJ4_v7k http://www.nanopub.org/nschema#hasProvenance https://w3id.org/np/RA3o90XgFx_gbp6k69qT8WA1MaaEFwaILFWnfwEJ4_v7k/provenance https://w3id.org/np/RA3o90XgFx_gbp6k69qT8WA1MaaEFwaILFWnfwEJ4_v7k http://www.nanopub.org/nschema#hasPublicationInfo https://w3id.org/np/RA3o90XgFx_gbp6k69qT8WA1MaaEFwaILFWnfwEJ4_v7k/pubinfo https://w3id.org/np/RA3o90XgFx_gbp6k69qT8WA1MaaEFwaILFWnfwEJ4_v7k http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication https://w3id.org/np/RA3o90XgFx_gbp6k69qT8WA1MaaEFwaILFWnfwEJ4_v7k/assertion https://w3id.org/np/RA3o90XgFx_gbp6k69qT8WA1MaaEFwaILFWnfwEJ4_v7k/_b1 http://schema.org/alternateName aaval https://w3id.org/np/RA3o90XgFx_gbp6k69qT8WA1MaaEFwaILFWnfwEJ4_v7k/_b1 http://schema.org/identifier short_name https://w3id.org/np/RA3o90XgFx_gbp6k69qT8WA1MaaEFwaILFWnfwEJ4_v7k/_b1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type https://w3id.org/peh/terms/ContextAlias https://w3id.org/np/RA3o90XgFx_gbp6k69qT8WA1MaaEFwaILFWnfwEJ4_v7k/_b1 https://w3id.org/peh/terms/hasContext https://ror.org/04gq0w522 https://w3id.org/peh/biochementities/RA3o90XgFx_gbp6k69qT8WA1MaaEFwaILFWnfwEJ4_v7k http://purl.org/dc/terms/isPartOf https://w3id.org/spaces/biochementity/r/vocabulary https://w3id.org/peh/biochementities/RA3o90XgFx_gbp6k69qT8WA1MaaEFwaILFWnfwEJ4_v7k http://schema.org/alternateName AAVal https://w3id.org/peh/biochementities/RA3o90XgFx_gbp6k69qT8WA1MaaEFwaILFWnfwEJ4_v7k http://schema.org/alternateName AAVal https://w3id.org/peh/biochementities/RA3o90XgFx_gbp6k69qT8WA1MaaEFwaILFWnfwEJ4_v7k http://schema.org/comment comments: Should parent compound not be acrylamide? INCHIKEY Does not seem to correspond to the correct compound Pubchem link to AAVal: https://pubchem.ncbi.nlm.nih.gov/substance/341427830 vs Pubchem link to related compound with INCHI key specified here: https://pubchem.ncbi.nlm.nih.gov/compound/N-_3-Amino-3-oxopropyl_-L-valine --> chemical structure is not the same so I don't know if these are the same compounds? feedback_epi team: Yes assigning Acrylamide as parent compound seems correct to me. Because Acrylamide is the substance a human is exposed to, and we can measure GAVAL and AAVAL to reflect that exposure. GA‑Val (GAVAL) and AA‑Val (AAVAL) — are both well‑established biomarkers of exposure to acrylamide and its metabolite glycidamide. These adducts form when the reactive compounds bind to the N‑terminal valine of hemoglobin. Core attribution - AAVAL (N‑(2‑carbamoylethyl)valine) reflects exposure to acrylamide, the parent compound. - GAVAL (N‑(2‑carbamoyl‑2‑hydroxyethyl)valine) reflects exposure to glycidamide, which is the epoxide metabolite formed when acrylamide is metabolized via CYP2E1. This relationship is well documented: acrylamide is converted to glycidamide, and both acrylamide and glycidamide form hemoglobin adducts that can be used to reconstruct exposure. source: https://pmc.ncbi.nlm.nih.gov/articles/PMC5696489/ Moreover, AA and GA react with plasma and other proteins, such as hemoglobin (Hb). 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